- 基本信息
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导师姓名：
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田华
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学科代码：
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100214
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性别：
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男
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学科名称：
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肿瘤学
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培养单位：
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附属仁济医院
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三级学科
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导师类型：
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博士生导师
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专业领域名称：
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联系方式：
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专业领域代码：
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邮编：
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邮箱地址：
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tianhua722@163.com
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- 研究方向 (点击浏览详细信息)
- 社会任职
- 科研项目
| 81972581 | AKR1C3对肝癌细胞增殖和转移的调控及其分子机制研究 | 国家自然科学基金 |
2020-01~2023-12
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57万元
| 课题负责人 |
| 201940429 | SNX5通过EGFR通路调控肝癌细胞增殖和转移的机制研究 | 上海市卫健委卫生行业临床研究专项 |
2020-01~2022-12
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10万元
| 课题负责人 |
| 19ZR1452800 | AKR1C3对肝癌细胞转移的调控及其分子机制研究 | 上海市自然科学基金 |
2019-07~2022-06
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20万元
| 课题负责人 |
| 201540107 | ITGA1在肝癌中的表达及其调控机制的研究 | 上海市卫计委课题面上项目 |
2016-01~2018-12
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5万元
| 课题负责人 |
| 81472570 | 锌α2糖蛋白在肝细胞癌中的表达调控及其作用机制研究 | 国家自然科学基金面上项目 |
2015-01~2018-12
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75万元
| 课题负责人 |
| 12ZR1430000 | RRM2B对肝细胞癌AZGP1基因的表达调控及其分子机制的研究 | 上海市自然科学基金面上项目 |
2012-07~2015-06
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10万元
| 课题负责人 |
| 20114169 | p53R2在肝癌中的表达及其调控机制的研究 | 上海市卫生局科研课题面上项目 |
2012-01~2014-12
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3万元
| 课题负责人 |
| 20110073120105 | 核糖核苷酸还原酶在肝细胞肝癌中的差异表达及其调控机制的研究 | 教育部博士点基金 |
2012-01~2014-12
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4万元
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- 学术论文
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Qingqing Zhou , Feng Qi , Chenfei Zhou , Jun Ji , Jinling Jiang , Chao Wang , Qianfu Zhao , Yangbing Jin , Junwei Wu , Qu Cai ,, Jun Zhang
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VPS35 promotes gastric cancer progression through Integrin/FAK/Src signaling-mediated IL-6/STAT3 pathway activation in a YAP-dependent manner
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Oncogene
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2024
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43(2):106-122
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Chen J, Zhang J, Tian W, Ge C, Su Y, Li J,
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AKR1C3 suppresses ferroptosis in hepatocellular carcinoma through regulation of YAP/SLC7A11 signaling pathway.
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Mol Carcinog
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2023
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62(6):833-844
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Zhou Q, Li J, Ge C, Chen J, Tian W,
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SNX5 suppresses clear cell renal cell carcinoma progression by inducing CD44 internalization and epithelial-to-mesenchymal transition
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Mol Ther Oncolytics
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2022
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17; 24: 87–100
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Zhan W, Tian W, Zhang W,, Sun T
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ANGPTL4 attenuates palmitic acid-induced endothelial cell injury by increasing autophagy
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Cell Signal
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2022
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98:110410
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Sun T, Wei L,, Zhan W, Ma H, Nie D, Wang S, Chen X, Tang G.
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Novel PET/CT tracers for targeted imaging of membrane receptors to evaluate cardiomyocyte apoptosis and tissue repair process in a rat model of myocardial infarction
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Apoptosis
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2021
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26(7-8):460-473
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Huang T, Tian W, Zhou Q, Li J, Jiang Z, Chen J, Ge C,
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Upregulation of Rpn10 promotes tumor progression via activation of the NF-κB pathway in clear cell renal cell carcinoma
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Acta Biochim Biophys Sin (Shanghai) .
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2021
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53(8):988-996
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Zhou Q, Tian W, Jiang Z, Huang T, Ge C, Liu T, Zhao F, Chen T, Cui Y, Li H, Yao M, Li J,
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A positive feedback loop of AKR1C3-mediated activation of NF-κB and STAT3 facilitates proliferation and metastasis in hepatocellular carcinoma
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Cancer Research
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2021
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81:1361–74
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Wei L, Zhou Q,, Su Y, Fu GH, Sun T
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Integrin β3 promotes cardiomyocyte proliferation and attenuates hypoxia-induced apoptosis via regulating the PTEN/Akt/mTOR and ERK1/2 pathways.
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Int J Biol Sci
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2020
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16(4):644-654
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Cao Y, Wang J,, Fu GH
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Mitochondrial ROS accumulation inhibiting JAK2/STAT3 pathway is a critical modulator of CYT997-induced autophagy and apoptosis in gastric cancer
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J Exp Clin Cancer Res
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2020
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39(1):119
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Zhou Q, Huang T, Jiang Z, Ge C, Chen X, Zhang L, Zhao F, Zhu M, Chen T, Cui Y, Li H, Yao M, Li J,
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Upregulation of SNX5 predicts poor prognosis and promotes hepatocellular carcinoma progression by modulating the EGFR-ERK1/2 signaling pathway
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Oncogene
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2020
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39:2140-2155
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Jiang Z, Zhou Q, Ge C, Yang J, Li H, Chen T, Xie H, Cui Y, Shao M, Li J,
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Rpn10 promotes tumor progression by regulating hypoxia-inducible factor 1 alpha through the PTEN/Akt signaling pathway in hepatocellular carcinoma
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Cancer Lett
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2019
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20:447:1-11
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Hou H, Ge C, Sun H, Li H, Li J,
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Tunicamycin inhibits cell proliferation and migration in hepatocellular carcinoma via suppression of CD44s and the ERK1/2 pathway
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Cancer Sci
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2018
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109:1088-1100
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Liu Zheng, Yang Jing, Ge Chao, Zhao Fangyu, Li Hong, Yao Ming, Li Jinjun,
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Inhibitor of binding/differentiation 2 (Id2) is regulated by CCAAT/enhancer-binding protein-α (C/EBPα) and promotes the proliferation of hepatocellular carcinoma
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Am J Cancer Res
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2018
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8(11):2254-2266
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Yifan Su,, Lijiang Wei, Guo-hui Fu, Ting Sun
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Integrin β3 inhibits hypoxia induced apoptosis in cardiomyocytes
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Acta Biochimica et Biophysica Sinica
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2018
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50(7):658-665
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, Ge C, Zhao F, Zhu M, Zhang L, Huo Q, Li H, Chen T, Xie H, Cui Y, Yao M, Li J
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Downregulation of AZGP1 by Ikaros and histone deacetylase promotes tumor progression through the PTEN/Akt and CD44s pathways in hepatocellular carcinoma
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Carcinogenesis
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2017
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38(2):207-217
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, Chao Ge, Hong Li, Fangyu Zhao, Helei Hou, Taoyang Chen, Guoping Jiang, Haiyang Xie, Ying Cui, Ming Yao, Jinjun Li.
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Ribonucleotide reductase M2B inhibits cell migration and spreading by early growth response protein 1-mediated phosphatase and tensin homolog/Akt1 pathway in hepatocellular carcinoma.
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Hepatology
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2014
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59(4):1459-70
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Sun T,, Feng YG, Zhu YQ, Zhang WQ.
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Egr-1 promotes cell proliferation and invasion by increasing β-catenin expression in gastric cancer.
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Dig Dis Sci
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2013
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58(2):423-30
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Qiuhua Xu, Ting Sun,, Changqian Wang, Huihong Zhou
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Ultrasound-mediated VEGF-C gene microbubble transfection inhibits growth of MCF-7 breast cancer cells.
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Oncol Res
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2012
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20(7)297-301
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, Ning Zhang, Wen-Hao Suo, Ting Wang, Ling-Jun Song, Jun Wu, Qiang Liu, Wei-Wei Shen, Guo-Hui Fu
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Gastrin suppresses the interdependent expression of p16 and anion exchanger 1 favouring growth inhibition of gastric cancer cells.
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Int J cancer
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2010
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127(6): 1462-1474
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