- 基本信息
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导师姓名：
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黄陈
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学科代码：
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100210
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性别：
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男
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学科名称：
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外科学
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培养单位：
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附属第一人民医院
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三级学科
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普外
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导师类型：
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博士生导师
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专业领域名称：
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外科学 专业学位
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联系方式：
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手机：13381758371
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专业领域代码：
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105111
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邮编：
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邮箱地址：
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richard-hc@hotmail.com
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- 研究方向 (点击浏览详细信息)
- 社会任职
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中国医师协会外科医师分会专业信息传播和教育专家工作组专家委员
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上海市抗癌协会肿瘤精准治疗委员会委员
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中国临床肿瘤学会胃癌专业委员会委员
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《中华全科医学》、《中华普通外科学文献-电子版》、《中国普通外科杂志》、《现代肿瘤医学》、《现代生物医学进展》等核心期刊编委
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中国医师协会外科医师分会结直肠外科专家工作组专家委员
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中国医师协会结直肠肿瘤专委会委员
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上海市医学会普外科分会委员
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上海市医学会普外科分会胃肠外科学组委员
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上海肿瘤能量治疗协同创新中心-胃肠肿瘤智能诊断与治疗研究中心主任
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中国医师协会外科医师分会上消化道外科专家工作组专家委员
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中国临床肿瘤学会青年专家委员会委员
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上海市医师协会普外科医师分会委员
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上海市抗癌协会胃肠肿瘤腹腔镜专委会常务委员
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中国医师协会外科医师分会机器人外科专家工作组专家委员
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中国医师协会外科医师分会胃肠间质瘤诊疗专家工作组专家委员
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上海市抗癌协会胃癌专委会常务委员
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中国医师协会外科医师分会肛肠外科专家工作组专家委员
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上海市抗癌协会腔镜外科学组委员
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上海市抗癌协会胃癌专委会常委
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- 科研项目
| | 特色国家领军人才培养计划 | 上海市第一人民医院 |
2022-01~2024-12
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100万元
| 课题负责人 |
| 82072662 | 缺氧诱导的circIREB2通过编码多肽IREB2-268aa促进胃癌EMT和转移的机制研究 | 国家自然科学基金(面上项目） |
2021-01~2024-12
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55万元
| 课题负责人 |
| SHDC2020CR4022 | 基于AI技术的左右半结肠癌预后预测模型的建立 | 第二轮《促进市级医院临床技能与临床创新三年行动计划（2020-2022年）》重大临床研究项目 |
2020-10~2022-09
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50万元
| 课题负责人 |
| 1020302404 | 人工智能导引的腹腔镜恒压手术系统建立及其临床应用 | 上海理工大学、上海交大医工交叉重点项目 |
2020-07~2022-06
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20万元
| 课题负责人 |
| Y-Young2020-0458 | 基于AI与影像学建立结直肠癌术前综合评估体系 | 希思科-青年创新肿瘤研究基金 |
2020-01~2022-12
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5万元
| 课题负责人 |
| | 人工智能引导的大肠癌精准治疗体系研究 | 上海市松江科技攻关项目 |
2020-01~2022-12
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10万元
| 课题负责人 |
| 20191425 | 结直肠癌新型预后预测模型建立 | 上海交通大学医学院高峰高原计划-“研究型医师”（第二轮） |
2019-07~2022-06
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100万元
| 课题负责人 |
| 81772526 | circ_0001790/miR-509-3-5P/GINS4通路在胃癌生长中的作用及其机制 | 国家自然科学基金（面上项目） |
2018-01~2021-12
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57万元
| 课题负责人 |
| YG2017MS28 | ncRNA用于胃癌诊断和监测生物芯片研制 | 上海交通大学医工交叉研究基金 |
2018-01~2020-12
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20万元
| 课题负责人 |
| 20161425 | 胃癌患者血液中ncRNA的表达与胃癌发生发展及预后的临床研究 | 上海交通大学医学院高峰高原计划“研究型医师”项目 |
2017-01~2019-12
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100万元
| 课题负责人 |
| UF201419 | 乌司他丁在胰腺癌患者术后胰瘘和预后中的临床应用研究 | 天普研究基金 |
2016-01~2017-12
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10万元
| 课题负责人 |
| 14411966800 | FoxM1亚型在胃癌诊断和预后中的临床应用 | 上海市科委 |
2014-10~2017-09
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20万元
| 课题负责人 |
| XYQ2013092 | FoxM1c在胰腺癌EMT和转移中的作用及其机制研究 | 上海市卫生和计划生育委员会 |
2014-01~2017-01
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60万元
| 课题负责人 |
| 13PJD024 | FoxM1亚型在胰腺癌诊断和预后中的应用研究 | 上海市浦江人才计划 |
2013-09~2015-08
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20万元
| 课题负责人 |
| | 上海交通大学晨星青年学者计划 | 上海交通大学 |
2013-01~2015-12
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8万元
| 课题负责人 |
| | 上海交通大学医学院新百人计划 | 上海交通大学医学院 |
2013-01~2015-12
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10万元
| 课题负责人 |
| 2012040 | 上海人才发展资金 | 上海市人力资源和社会保障局人才计划项目 |
2012-10~2014-09
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10万元
| 课题负责人 |
| 81210108027 | 调控Caveolin-1对胰腺癌转移和EMT的影响及其机制研究 | 国家自然科学基金对外交流与合作项目 |
2012-07~2012-12
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2.1万元
| 课题负责人 |
| 81101844 | Caveolin-1 在胰腺癌转移和EMT 中的作用及其机制研究 | 国家自然科学基金青年科学基金项目 |
2012-01~2014-12
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20万元
| 课题负责人 |
| 09QA1404600 | 调控STAT3信号通路对胰腺癌侵袭转移作用及其机制的研究 | 上海市科委人才计划项目（启明星计划） |
2009-07~2011-06
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15万元
| 课题负责人 |
- 学术论文
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Sun L, Zhang Y, Yang B, Sun S, Zhang P, Luo Z, Feng T, Cui Z, Zhu T, Li Y, Qiu Z, Fan G,
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Lactylation of METTL16 promotes cuproptosis via m6A-modification on FDX1 mRNA in gastric cancer
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Nature Communications
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2023
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13(1):5637
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Fu Z, Zhang P, Zhang R, Zhang B, Xiang S, Zhang Y, Luo Z,
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Novel hypoxia-induced HIF1α-circTDRD3-positive feedback loop promotes the growth and metastasis of colorectal cancer
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Oncogene
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2023
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42(3):238-252
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Xu Y,
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Progress and application of epitranscriptomic m6A modification in gastric cancer
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RNA Biol
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2022
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19(1):885-896
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Zhang J, Zhang J, Fu Z, Zhang Y, Luo Z, Zhang P, Xu Y,
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CHREBP suppresses gastric cancer progression via the cyclin D1-Rb-E2F1 pathway
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Cell Death Discov
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2022
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8(1):300
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Li T, Yang Y, Wu W, Fu Z, Cheng F, Qiu J, Li Q, Zhang K, Luo Z, Qiu Z,
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Prognostic implications of ENE and LODDS in relation to lymph node-positive colorectal cancer location
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Transl Oncol
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2021
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14(11):101190
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Xu Y, Zhang P, Zhang K,
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The application of CA72-4 in the diagnosis, prognosis, and treatment of gastric cancer
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Biochim Biophys Acta Rev Cancer
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2021
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1876(2):188634
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Li T, Yu Z, Yang Y, Fu Z, Chen Z, Li Q, Zhang K, Luo Z, Qiu Z,
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Rapid multi-dynamic algorithm for gray image analysis of the stroma percentage on colorectal cancer
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J Cancer
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2021
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12(15):4561-4573
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Chen W, Zhang K, Yang Y, Guo Z, Wang X, Teng B, Zhao Q,, Qiu Z
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MEF2A-mediated lncRNA HCP5 Inhibits Gastric Cancer Progression via MiR-106b-5p/p21 Axis
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Int J Biol Sci
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2021
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17(2):623-634
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Zhang Y, Zhang P, Rong Z,
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One stomach, two subtypes of carcinoma—the differences between distal and proximal gastric cancer
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Gastroenterology Report
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2021
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9(6):489–504
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Zhang P, Zhang Z, Fu Y, Zhang Y, Washburn MP, Florens L, Wu M,, Hou Z, Mohan M
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K63-linked ubiquitination of DYRK1A by TRAF2 alleviates Sprouty 2-mediated degradation of EGFR
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Cell Death Dis
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2021
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12(6):608
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Rao X, Liu X, Liu N, Zhang Y, Zhang Z, Zhou L, Han G, Cen R, Shi N, Zhu H, Gong H,, Ji Q, Li Q
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Long noncoding RNA NEAT1 promotes tumorigenesis in H. pylori gastric cancer by sponging miR-30a to regulate COX-2/BCL9 pathway
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Helicobacter
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2021
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26(6):e12847
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Yu Z, Rong Z, Sheng J, Luo Z, Zhang J, Li T, Fu Z, Qiu Z,
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Aberrant non-coding RNAs expressed in gastric cancer and its diagnostic value
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Frontiers in oncology
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2021
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11:2584
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Yang Y, Guo Z, Chen W, Wang X, Cao M, Han X, Zhang K, Teng B, Cao J, Wu W, Cao P,, Qiu Z
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M2 Macrophage-Derived Exosomes Promote Angiogenesis and Growth of Pancreatic Ductal Adenocarcinoma by Targeting E2F2
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Molecular Therapy
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2021
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29(3):1226-1238
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Rong Z, Luo Z, Fu Z, Zhang P, Li T, Zhang J, Zhu Z, Yu Z, Li Q, Qiu Z,
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The novel circSLC6A6/miR-1265/C2CD4A axis promotes colorectal cancer growth by suppressing p53 signaling pathway
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J Exp Clin Cancer Res
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2021
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40(1):324
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Luo Z, Fu Z, Li T, Zhang Y, Zhang J, Yang Y, Yang Z, Li Q, Qiu Z,
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Development and validation of the individualized prognostic nomograms in patients with right- and left-sided colon cancer
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Front Oncol
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2021
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11:709835
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Rong Z, Luo Z, Zhang J, Li T, Zhu Z, Yu Z, Fu Z, Qiu Z,
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GINS4, a prognostic biomarker and reversely mediated by KLF4, promotes the growth of colorectal cancer
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Cancer Science
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2020
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111(4):1203-1217
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Luo Z, Rong Z, Zhang J, Zhu Z, Yu Z, Li T, Fu Z, Qiu Z,
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Circular RNA circCCDC9 acts as a miR-6792-3p sponge to suppress the progression of gastric cancer through regulating CAV1 expression
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Molecular Cancer
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2020
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19:86.
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Guo Z, Wang X, Yang Y, Chen W, Zhang K, Teng B,, Zhao Q, Qiu Z
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Hypoxic Tumor-Derived Exosomal Long Noncoding RNA UCA1 Promotes Angiogenesis via miR-96-5p/AMOTL2 in Pancreatic Cancer
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Mol Ther Nucleic Acids
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2020
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22:179-195
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Zhu Z, Yu Z, Rong Z, Luo Z, Zhang J, Qiu Z,
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The novel GINS4 axis promotes gastric cancer growth and progression by activating Rac1 and CDC42
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Theranostics
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2019
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9(26):8294-8311
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Zhang J, Zhu ZL, Wu HJ, Yu ZL, Rong ZY, Luo Z, Xu YW, Huang KJ, Qiu ZJ,
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PODXL, negatively regulated by KLF4, promotes the EMT and metastasis and serves as a novel prognostic indicator of gastric cancer.
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Gastric cancer
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2019
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22(1):48-59
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Zhonglin Zhu,Zeyin Rong,Zai Luo,Zhilong Yu,Jing Zhang,Zhengjun Qiu,
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Circular RNA circNHSL1 promotes gastric cancer progression through the miR-1306-3p/SIX1/Vimentin aixs
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Molecular Cancer
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2019
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18:126
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Wang X, Luo G, Zhang K, Cao J,, Jiang T, Liu B, Su L, Qiu Z.
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Hypoxic tumor-derived exosomal miR-301a mediates M2 macrophage polarization via PTEN/PI3Kγ to promote pancreatic cancer metastasis
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Cancer Research
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2018
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78(16):4586-4598
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Li B,
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Regulation of EMT by STAT3 in gastrointestinal cancer
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International Journal of Oncology
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2017
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50(3): 753-767
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Zhang J, Niu YY,
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Role of FoxM1 in the Progression and Epithelial to Mesenchymal Transition of Gastrointestinal Cancer
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Recent Pat Anticancer Drug Discov
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2017
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12(3):247-259
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Zhang KD, Yang G, Wu WD, Zhang J, Xia X, Jiang T, Cao J, Huang KJ, Qiu ZJ,
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Decreased expression of caveolin-1 and E-cadherin with the clinicopathologic features of gastric cancer and the EMT process
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Anti-Cancer Drug Discovery
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2016
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11(2):236-244
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, Cai Z, Huang M, Mao C, Zhang Q, Lin Y, Zhang X, Tang B, Chen Y, Wang X, Qian Z, Ye L, Peng Y, Xu H
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miR-219-5p Modulates Cell Growth of PapillaryThyroid Carcinoma by Targeting Estrogen Receptor α
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J Clin Endocrinol Metab
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2015
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100(2):E204-13
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Wang H,
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FOXM1 and its Oncogenic Signaling in Gastric Cancer
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Recent patents on anti-cancer drug discovery
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2015
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10(3):270-9
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, Du J, Xie K
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FOXM1 and its oncogenic signaling in pancreatic cancer pathogenesis
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Biochim Biophys Acta
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2014
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1845(2):104-116
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, Xie D, Cui J, Li Q, Gao Y, Xie K
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FOXM1c Promotes Pancreatic Cancer Epithelial-to-Mesenchymal Transition and Metastasis via Upregulation of Expression of the Urokinase Plasminogen Activator System
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Clin Cancer Res
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2014
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20(6):1477-1488
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Kong X, Li L, Li Z, Le X,, Jia Z, Cui J, Huang S, Wang L, Xie K
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Dysregulated expression of FOXM1 isoforms drives progression of pancreatic cancer
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Cancer Res
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2013
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73(13):3987-3996
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, Li HD, Wu WD, Jiang T, Qiu ZJ
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Regulation of miR-155 affects pancreatic cancer cell invasiveness and migration by modulating STAT3 signal pathway through SOCS1
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Oncology Reports
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2013
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30: 1223-1230
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Li D, Wei P, Peng Z,, Tang H, Jia Z, Cui J, Le X, Huang S, Xie K
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The Critical Role of Dysregulated FOXM1-PLAUR Signaling in Human Colon Cancer Progression and Metastasis
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Clin Cancer Res
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2013
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19(1):62-72.
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, Qiu Z, Wang L, Peng Z, Jia Z, Logsdon CD, Le X, Wei D, Huang S, Xie K
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A novel FoxM1-caveolin signaling pathway promotes pancreatic cancer invasion and metastasis
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Cancer Res
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2012
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72(3):655-65
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, Xie K
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Crosstalk of Sp1 and Stat3 signaling in pancreatic cancer pathogenesis
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Cytokine Growth Factor Rev
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2012
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23(1-2):25-35.
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, Yang G, Jiang T, Zhu G, Li H, Qiu Z
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The effects and mechanisms of blockage of STAT3 signaling pathway on IL-6 inducing EMT in human pancreatic cancer cells in vitro
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Neoplasma
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2011
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58(5),396-405.
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, Jiang T, Zhu L, Liu J, Cao J, Huang KJ, Qiu ZJ
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STAT3-targeting RNA interference inhibits pancreatic cancer angiogenesis in vitro and in vivo
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Int J Oncol
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2011
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38(6):1637-1644.
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, Huang RX, Qiu ZJ
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Natural orifice transluminal endoscopic surgery: new minimally invasive surgery come of age
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World J Gastroenterol
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2011
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17(39):4382-8.
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, Huang RX, Jiang T, Huang K, Cao J, Qiu Z
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Laparoscopic and open resection for colorectal cancer: an evaluation of cellular immunity
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BMC Gastroenterology
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2010
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10:127
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, Yang G, Jiang T, Huang K, Cao J, Qiu Z.
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Effects of IL-6 and AG490 on regulation of Stat3 signaling pathway and invasion of human pancreatic cancer cells in vitro.
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J Exp Clin Cancer Res
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2010
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29:51
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, Cao J, Huang KJ, Zhang F, Jiang T, Zhu L, Qiu ZJ
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Inhibition of STAT3 activity with AG490 decreases the invasion of human pancreatic cancer cell in vitro
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Cancer Science
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2006
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97(12):1417-1423.
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