• 基本信息
    导师姓名: 钟华 学科代码: 100201
    性别: 学科名称: 内科学
    培养单位: 附属仁济医院 三级学科 血液病
    导师类型: 硕士生导师 专业领域名称: 内科学 专业学位
    联系方式: 上海市闵行区江月路2000号仁济医院(南院)住院部10楼西 专业领域代码: 105101
    邮编: 201112 邮箱地址: zhh_lj@hotmail.com
  • 研究方向 (点击浏览详细信息)
  • 社会任职
  • 科研项目
    项目编号项目名称课题来源起止年月批准经费承担职责
    19ZR1431400􏰖􏰗􏰘􏰙􏰚􏰛􏰜􏰝􏰞􏰟􏰠􏰡􏰢􏰣􏰤􏰞􏰥􏰟􏰎􏰦􏰧􏰨􏰩􏰪 􏰫􏰬􏰭􏰝􏰯􏰰􏰱􏰲􏰞􏰙􏰳􏰴􏰒􏰵􏰶􏰷􏰸􏰹􏰺􏰻􏰼􏰽􏰾􏰿􏰖􏰗􏰘􏰙􏰚􏰛􏰜􏰝􏰞􏰟􏰠􏰡􏰢􏰣􏰤􏰞􏰥􏰟􏰎􏰦􏰧􏰨􏰩􏰪 􏰫􏰬􏰭􏰮􏰞􏰝􏰯􏰰􏰱􏰲􏰞􏰙􏰳􏰴􏰒􏰵􏰶􏰷􏰸􏰹􏰺􏰻􏰼􏰽􏰾􏰿G-CSF通过MAPK途径调控AQP9蛋白表达增加 老年AML病人对 AS2O3作用敏感性相关机制研究上海市科委 2019-07~2022-06 20万元  课题负责人
    18-061白血病细胞和骨髓微环境相互作用对化疗药物的影响仁济医院南院国家自然科学基金培育项目 2017-11~2020-10 15万元  课题负责人
    81270626miR-146a 调控CXCR4/Smad4 蛋白表达在含G-CSF 的预激方 案治疗急性髓性白血病中的作用国家自然科学基金面上项目 2013-01~2016-12 70万元  课题负责人
    ZYSNXD-CC-ZDYJ001刺五加注射液中有效药物成分对急性髓性白血病体内外作用机制研究卫生局中医药三年行动计划 2011-12~2014-12 40万元  课题负责人
    09ZR1418400miRNA146a对急性髓性白血病Smad4表达及细胞增殖的调控作用上海市科委 2009-8~2011-7 10万元  课题负责人
    PW2009D-5弥漫大B细胞淋巴瘤的规范诊治及临床预后因素分析浦东新区卫生局 2009-07~2012-06 14万元  课题负责人
  • 学术论文
    作者论文标题期刊名出版年卷期页码
    Yunhe Liu, Ning Yang, Xueqing Peng, Gang Liu,, Lei Liu  One-lincRNA and five-mRNA based signature for prognosis of multiple myeloma patients undergoing proteasome inhibitors therapy  Biomedicine & Pharmacotherapy  2019  118:109254 
    Andi Wang and Hua Zhong  Roles of the bone marrow niche in hematopoiesis, leukemogenesis, and chemotherapy resistance in acute myeloid leukemia  hematology  2018  14:1-11 
    Xin Li, Lan Xu, Xianfu Sheng, Jiayi Cai, Jia Liu, Tingyu Yin, Fei Xiao, Fangyuan Chen,  Upregulated microRNA-146a expression induced by granulocyte colony-stimulating factor enhanced low-dosage chemotherapy response in aged acute myeloid leukemia patients  Experimental Hematology  2018  68:66−79 
    Bin Wu, Maobai Liu, Te Li, Houwen Lin,  An economic analysis of high-dose imatinib, dasatinib, and nilotinib for imatinib-resistant chronic phase chronic myeloid leukemia in China A CHEERS-compliant article  MEDICINE  2017  96:29 
    Jun-Ying Wang, Shuang Ye and Hua Zhong  The role of bone marrow microenvironment in platelet production and their implications for the treatment of thrombocytopenic diseases  hematology  2017  22(10):630-639. 
    XIANFU SHENG,, HAIXIA WAN, JIHUA ZHONG and FANGYUAN CHEN  Granulocyte colony-stimulating factor inhibits CXCR4/SDF-1?? signaling and overcomes stromal-mediated drug resistance in the HL-60 cell line  EXPERIMENTAL AND THERAPEUTIC MEDICINE   2016  12: 396-404 
    Xin Li,  The diagnosis, prognosis, and therapeutic application of MicroRNAs in haematological malignancies  Hematology  2016  21(5):263-71 
    Qing-yuan Wang,, Fang-yuan Chen, Min-yue Zhang, Jia-yi Cai, Ji-hua Zhong  A preliminary study on epigenetic regulation of Acanthopanax senticosus in leukemia cell lines  Experimental Hematology  2016  44(6):466-73 
    Qing-yuan Wang,  Epigenetic programming contributes to development of drug resistance in hematologicalmalignancies   Frontiers in Bioscience, Landmark  2015  20, 728-742, 
    Lan Xu,, HaixiaWan, Fang-yuan Chen, Jihua Zhong, Fei Xiao, Jia Liu,Lijing Shen  miR-146a Expression Level as a Novel Putative Prognostic Marker for Acute Promyelocytic Leukemia  Disease Markers  2014  Volume 2014, Article ID 150604, 9 pages 
    ,LAN XU*,JI-HUA ZHONG,FEI XIAO,QIANG LIU,HONG-HUI HUANG,FANG-YUAN CHEN  Clinical and prognostic significance of miR-155 and miR-146a expression levels in formalin-fixed/paraffin-embedded tissue of patients with diffuse large B-cell lymphoma  EXPERIMENTAL AND THERAPEUTIC MEDICINE  2012  3:763-770 
    ,Chun Wang,Fang-yuan Chen  MicroRNA-146a and hemopoietic disorders  IJH  2011  94(3):224-229 
    ,Hai-rong Wang,Shuang Yang,Fang-yuan Chen,Ji-hua Zhong  MiR-146a inhibits human acute promyelocytic leukemia cell line proliferation via TGF?/Smad signal transduction pathway during retinoid acid induced differentiation.  IJH  2010  92(1):129-135 
    , Fang-yuan Chen, Hai-rong Wang , Jia-yao Lin, Rong Xu,Ji-hua Zhong,Hong-hui Huang  Modification of TGF-β1 signaling pathway during NB4 cells differentiation by all- trans retinoid acid inductio  IJH  2009  89(4):438-444