• 基本信息
    导师姓名: 邹强 专业代码: 100100
    性别: 专业名称: 基础医学
    培养单位: 基础医学院 三级学科/
    专业领域:
    导师类型: 博士生导师 专业学位导师:
    联系方式: 021-64666150
    邮箱地址: Qzou1984@126.com 邮编: 200025
  • 研究方向 (点击浏览详细信息)
  • 社会任职
     
    Journal of Molecular Cell Biology、Protein & Cell、PLoS ONE等杂志审稿人
  • 科研项目
    项目编号项目名称课题来源起止年月批准经费承担职责
    31870884泛素连接酶ZFP91在CD8+T细胞抗肿瘤功能中的调控机制国家自然科学基金面上项目 2019-01~2022-12 60万元  课题负责人
    2018YQ08泛素连接酶ZFP91调控免疫耐受与肠癌发生的机制研究上海市卫生计生系统“优青计划” 2018-07~2021-06 30万元  课题负责人
    31670896TRAF3IP3调控T细胞活性与肿瘤免疫的分子机制国家自然科学基金面上项目 2017-01~2018-12 25万元  课题负责人
    第十二批国家“千人计划”青年人才调控肿瘤免疫的分子机制中组部“青年千人计划” 2016-09~2019-09 200万元  课题负责人
    16QA1403300MDM2对肿瘤免疫反应中T细胞活性影响的研究上海市科委启明星计划 2016-04~2019-03 40万元  课题负责人
  • 学术论文
    作者论文标题期刊名出版年卷期页码
    Yu X#, Lao Y#, Teng X-L#, Li S, Zhou Y, Wang F, Guo X, Deng S, Chang Y, Wu X, Liu Z, Chen L, Lu L, Cheng J, Li B, Su B, Jiang J, Li H-B*, Huang C*, Yi J*,  SENP3 maintains the stability and function of regulatory T cells via BACH2 deSUMOylation  Nature Communications  2018  9:3157 
    Yu X#, Teng X-L#, Wang F#, Zheng Y#, Qu G, Zhou Y, Hu Z, Wu Z, Chang Y, Chen L, Li H-B, Su B, Lu L*, Liu Z*, Sun S-C*,  Metabolic control of regulatory T cell stability and function by TRAF3IP3 at the lysosome  The Journal of Experimental Medicine  2018  215(9): 2463-2476 
    Xiao Y#,, Xie X#, Liu T, Li H, Jie Z, Jin J, Hu H, Manyam G, Zhang L, Cheng X, Wang H, Marie I, Levy D, Watowich S, and Sun SC  The kinase TBK1 functions in dendritic cells to regulate T cell homeostasis, autoimmunity, and antitumor immunity  The Journal of Experimental Medicine  2017  214(5): 1493-1507 
    Jin J#, Xie X#, Xiao Y, Hu H,, Cheng X, Sun SC  Epigenetic regulation of the expression of Il12 and Il23 and autoimmune inflammation by the deubiquitinase Trabid  Nature Immunology   2016  17(3):259-68 
    Hu H#, Wang H#, Xiao Y, Jin J, Chang JH,, Xie X, Cheng X, Sun SC  Otud7b facilitates T cell activation and inflammatory responses by regulating Zap70 ubiquitination  The Journal of Experimental Medicine   2016  213(3):399-414 
    , Jin J, Xiao Y, Zhou X, Hu H, Cheng X, Kazimi N, Ullrich S, Sun SC  T cell intrinsic USP15 deficiency promotes excessive IFN-γ production and an immunosuppressive tumor microenvironment in MCA-induced fibrosarcoma  Cell Reports  2015  13(11):2470-9 
    , Jin J, Xiao Y, Hu H, Zhou X, Jie Z, Xie X, Li J, Cheng X, Sun SC  T cell development involves TRAF3IP3-mediated ERK signaling in the Golgi  The Journal of Experimental Medicine  2015  212(8):1323-36 
    Jin J, Xiao Y, Hu H,, Li Y, Gao Y, Ge W, Cheng X, Sun SC  Proinflammatory TLR signalling is regulated by a TRAF2-dependent proteolysis mechanism in macrophages  Nature Communications  2015  6:5930 
    Jin J, Hu H, Li HS, Yu J, Xiao Y, Brittain GC,, Cheng X, Mallette FA, Watowich SS, Sun SC  Noncanonical NF-κB Pathway Controls the Production of Type I Interferons in Antiviral Innate Immunity  Immunity  2014  40(3):342-54 
    , Jin J, Hu H, Li HS, Romano S, Xiao Y, Nakaya M, Zhou X, Cheng X, Yang P, Lozano G, Zhu C, Watowich SS, Ullrich SE, Sun SC  USP15 stabilizes MDM2 to mediate cancer-cell survival and inhibit antitumor T cell responses  Nature Immunology  2014  15(6):562-70 
    , Wu B, Xue J, Fan X, Feng C, Geng S, Wang M, Wang B  CD8+ Treg cells suppress CD8+T cell-responses by IL-10-dependent mechanism during H5N1 influenza virus infection  European Journal of Immunology  2014  44(1):103-14 
    Xiao Y, Jin J, Chang M, Nakaya M, Hu H,, Zhou X, Brittain GC, Cheng X, Sun SC  TPL2 mediates autoimmune inflammation through activation of the TAK1 axis of IL-17 signaling  The Journal of Experimental Medicine  2014  211(8):1689-702