• 基本信息
    导师姓名： 苏青 学科代码： 100201
    性别： 男 学科名称： 内科学
    培养单位： 附属新华医院 三级学科 内分泌与代谢病
    导师类型： 博士生导师 专业领域名称： 内科学 专业学位
    联系方式： 专业领域代码： 105101
    邮编： 邮箱地址： suqing139@126.com
  • 研究方向 (点击浏览详细信息)
  • 社会任职
     
    中国医师协会内分泌代谢分会委员
    中华医学会糖尿病分会委员
    上海市医学会糖尿病专科分会副主任委员
  • 科研项目
    项目编号项目名称课题来源起止年月批准经费承担职责
    81970669AGEs-RAGE轴抑制β细胞胞葬在胰岛巨噬细胞极化失衡中的作用及机制研究国家自然科学基金面上项目 2020-01~2023-12 55万元  课题负责人
    81670743ChREBP在高糖诱导的胰岛β细胞去分化过程中的作用国家自然科学基金 2017-01~2020-12 58万元  课题负责人
  • 学术论文
    作者论文标题期刊名出版年卷期页码
    Zhang HM, Qin L, Sheng CS, Niu Y, Gu H, Lu S, Yang Z, Tian J,  ASCVD risk stratification modifies the effect of HbA1c on cardiovascular events among patients with type 2 diabetes mellitus with basic to moderate risk   BMJ Open Diabetes Res Care  2020  8(1):e000810 
    Ying Chen, Huandong Lin, Li Qin, Youli Lu, Lin Zhao, Mingfeng Xia, Jingjing Jiang, Xiaomu Li, Chen Yu, Geng Zong, Yan Zheng, Xin Gao,, and Xiaoying Li  Fasting Serum Fructose Levels Are Associated With Risk of Incident Type 2 Diabetes in Middle-Aged and Older Chinese Population  Diabetes Care  2020  Publish Ahead of Print 
    Dong X, Yu S, Wang Y, Yang M, Xiong J, Hei N, Dong B,, Chen J.  (Pro)renin receptor-mediated myocardial injury, apoptosis, and inflammatory response in rats with diabetic cardiomyopathy.  J Biol Chem  2019  294(20):8218-8226 
    Li B, Wu X, Chen H, Zhuang C, Zhang Z, Yao S, Cai D, Ning G,  miR199a-5p inhibits hepatic insulin sensitivity via suppression of ATG14-mediated autophagy  Cell Death Dis  2018  14;9(3):405 
    Zhang H, Niu Y, Gu H, Lu S, Zhang W, Li X, Yang Z, Qin L,  Low serum adiponectin is a predictor of progressing to non-alcoholic fatty liver disease  Journal of Clinical Laboratory Analysis  2018  2018 Nov 2:e22709 
    Ran H, Zhu Y, Deng R, Zhang Q, Liu X, Feng M, Zhong J, Lin S, Tong X,  Stearoyl-CoA desaturase-1 promotes colorectal cancer metastasis in response to glucose by suppressing PTEN  J Exp Clin Cancer Res  2018  37(1):54 
    , Liu J, Li P, Qian L, Yang W  Relative Contribution of Fasting and Postprandial Blood Glucose in Overall Glycemic Control: Post Hoc Analysis of a Phase IV Randomized Trial  Diabetes Ther  2018  9(3):987-999 
    Kong X, Lu AL, Yao XM, Hua Q, Li XY, Qin L, Zhang HM, Meng GX,  Activation of NLRP3 Inflammasome by Advanced Glycation End Products Promotes Pancreatic Islet Damage  Oxid Med Cell Longev.  2017  2017;2017:9692546 
    Lin N, Li XY, Zhang HM, Yang Z,  microRNA-199a-5p mediates high glucose-induced reactive oxygen species production and apoptosis in INS-1 pancreatic β-cells by targeting SIRT1  Eur Rev Med Pharmacol Sci.  2017  21(5):1091-1098 
    Zhang W, Yang Z, Niu Y, Li X, Zhu L, Lu S, Zhang H, Fan J, Ning G, Qin L,  Association of calf circumference with insulin resistance and non-alcohol fatty liver disease: the REACTION study  BMC Endocr Disord  2017  17(1):28 
    Zhang H, Dong Y,  Perinatal hypothyroidism modulates antioxidant defence status in the developing rat liver and heart  Can J Physiol Pharmacol  2017  95(2):185-189 
    Zhang HM, Zhou YQ, Dong Y,  Identification and functional characterization of a novel thyrotropin receptor mutation (V87L) in a Chinese woman with subclinical hypothyroidism  Exp Ther Med  2017  13(1):290-294 
    , Liu C, Zheng H, Zhu J, Li PF, Qian L, Yang WY  Comparison of insulin lispro mix 25 with insulin lispro mix 50 as insulin starter in Chinese patients with type 2 diabetes mellitus (CLASSIFY study): Subgroup analysis of a Phase 4 open-label randomized trial  J Diabetes  2017  9(6):575-585 
    Zhang H, Yang Z, Zhang W, Niu Y, Li X, Qin L,  White blood cell subtypes and risk of type 2 diabetes  J Diabetes Complications  2017  31(1):31-37 
    Qin L, Zhang W, Yang Z, Niu Y, Li X, Lu S, Xing Y, Lin N, Zhang H, Ning G, Fan J,  Impaired lung function is associated with non-alcoholic fatty liver disease independently of metabolic syndrome features in middle-aged and elderly Chinese  BMC Endocr Disord  2017  17(1):18 
    Zhang H, Yan C, Yang Z, Zhang W, Niu Y, Li X, Qin L,  Alterations of serum trace elements in patients with type 2 diabetes  J Trace Elem Med Biol.  2017  40:91-96 
    Deng R, Wu H, Ran H, Kong X, Hu L, Wang X,  Glucose-derived AGEs promote migration and invasion of colorectal cancer by up-regulating Sp1 expression  Biochim Biophys Acta  2017  1861(5 Pt A):1065-1074 
    Yang Z, Zhang W, Zhu L, Lin N, Niu Y, Li X, Lu S, Zhang H, Wang X, Wen J, Ning G, Qin L,  Resting heart rate and impaired glucose regulation in middle-aged and elderly Chinese people: a cross-sectional analysis  BMC Cardiovasc Disord  2017  17(1):246 
    Qin L, Yang Z, Zhang W, Gu H, Li X, Zhu L, Lu S, Xing Y, Zhang H, Niu Y, Ning G,  Metabolic syndrome and osteoporotic fracture: a population-based study in China  BMC Endocr Disord  2016  16(1):27 
    Niu Y, Zhang W, Yang Z, Li X, Fang W, Zhang H, Wang S, Zhou H, Fan J, Qin L,  Plasma osteoprotegerin levels are inversely associated with nonalcoholic fatty liver disease in patients with type 2 diabetes: A case-control study in China  Metabolism  2016  65(4):475-81 
    Qin L, Yang Z, Zhang W, Gu H, Lu S, Shi Q, Xing Y, Li X, Li R, Ning G,  Association between metabolic syndrome and lung function in middle-aged and elderly Chinese individuals  Diabetes Res Clin Pract  2015  Jun;108(3):e46-8 
    Zhang H, Yang Z, Zhang W, Niu Y, Li X, Qin L,  HIGHER SERUM OSTEOPROTEGERIN LEVELS IN SUBJECTS WITH THYROID NODULES  Endocr Pract  2015  Nov 23. [Epub ahead of print 
    Zhuhua Z, Zhiquan W, Zhen Y, Yixin N, Weiwei Z, Xiaoyong L, Yueming L, Hongmei Z, Li Q,  A novel mice model of metabolic syndrome: the high-fat-high-fructose diet-fed ICR mice  Exp Anim  2015  Oct 23;64(4):435-42 
    Niu Y, Zhang W, Yang Z, Li X, Wen J, Wang S, Zhang H, Wang X, Zhou H, Fang W,Qin L,  Association of plasma osteoprotegerin levels with the severity of lower extremity arterial disease in patients with type 2 diabetes  BMC Cardiovasc Disord  2015  Aug 11;15:86 
    Niu Y, Yang Z, Li X, Zhang W, Lu S, Zhang H, Chen X, Zhu L, Xing Y, Ning G, Qin L,  Association of osteoprotegerin with impaired glucose regulation and microalbuminuria: the REACTION study  BMC Endocr Disord.  2015  Dec 1;15(1):75 
    Zhang W, Yang Z, Li X, Wen J, Zhang H, Wang S, Wang X, Zhou H, Fang W, Qin L,  The functional Q84R polymorphism of TRIB3 gene is associated with diabetic nephropathy in Chinese type 2 diabetic patients  Gene  2015  Jan 25;555(2):357-61. 
    Kong X, Ma MZ, Huang K, Qin L, Zhang HM, Yang Z, Li XY,  Increased plasma levels of the methylglyoxal in patients with newly diagnosed type 2 diabetes.   J Diabetes  2014  Epub ahead of print 
    Qin L, Yang Z, Gu H, Lu S, Shi Q, Xing Y, Li X, Li R, Ning G,  Association between serum uric acid levels and cardiovascular disease in middle-aged and elderly Chinese individuals  BMC Cardiovasc Disord  2014  14(26):1471-2261 
    Jian W, Peng W, Xiao S, Li H, Jin J, Qin L, Dong Y,  Role of serum vaspin in progression of type 2 diabetes: a 2-year cohort study  PLoS One  2014  9(4):94-763 
    Kong X, Ma MZ, Qin L, Zhang Y, Li XY, Wang GD,, Zhang DY  Pioglitazone enhances the blood pressure-lowering effect of losartan via synergistic attenuation of angiotensin II-induced vasoconstriction  J Renin Angiotensin Aldosterone Syst  2014  Sep;15(3):259-70 
    Chen H, Wu L, Li Y, Meng J, Lin N, Yang D, Zhu Y, Li X, Li M, Xu Y, Wu Y, Tong X,  Advanced glycation end products increase carbohydrate responsive element binding protein expression and promote cancer cell proliferation.  Mol Cell Endocrinol.  2014  Sep;395(1-2):69-78. 
    Zhang HM, Lin N,, Su Q, Luo M.   Protein kinase cα is involved in impaired perinatal hypothyroid rat brain development.  Journal of neuroscience research  2013  92(2): 211-219 
    Jian WX, Peng WH, Jin J, Chen XR, Fang WJ, Wang WX, Qin L, Dong Y,  Association between serum fibroblast growth factor 21 and diabetic nephropathy.  Metabolism  2012  61(6): 853-859 
    Lin N, Zhang HM,  Advanced glycation end products induce pancreatic beta cell injury through oxidative stress.  Diabetes Metab  2012  38(3): 250-257 
    Du SC, Ge QM, Lin N, Dong Y,  ROS-mediated lipopolysaccharide-induced apoptosis in INS-1 cells by modulation of Bcl-2 and Bax.  Cell Mol Biol (Noisy-le-grand)  2012  58(sul): 1654-1659 
    Lin N, Chen HB, Zhang HM, Wan XY,  Mitochondrial ROS inhibition ameliorates endoplasmic reticulum stress in palmitate-induced INS-1 beta cell death  Endocrine  2012  42(1): 107-117 
    Zhang HM, Lin N, Dong Y,, Luo M.  Effect of perinatal thyroid hormone deficiency on expression of rat hippocampal conventional protein kinase C isozymes.  Mol Cell Biochem  2011  353(1-2): 65-71 
    Ge QM, Dong Y,  Effects of glucose and advanced glycation end products on oxidative stress in MIN6 cells  Cell Mol Biol (Noisy-le-grand)  2010  56 Suppl:OL1231-8 
    Ge QM, Dong Y, ZHANG HM,  Effects of intermittent high glucose on oxidative stress in endothelial cells.  Acta Diabetol  2009  Epub ahead of print 
    Zhang HM,, Luo M  Thyroid hormone regulates the expression of SNAP-25 during rat brain development  Mol Cell Biochem  2008  307:169-175 
    Dong Y, Sheng H, Chen X, Yin J,  Deletion of the V2 vasopressin receptor gene in two Chinese patients with nephrogenic diabetes insipidus  BMC Genet  2006  7:53-55